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Graduate School Faculty

Graduate School

Graduate School Leadership

Guy Salvesen, Ph.D.
Dean
Robert Rickert, Ph.D.
Associate Dean

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Salvatore Albani, M.D., Ph.D.

Director, Translational Research for Infectious and Inflammatory Disease Center
Professor, Infectious and Inflammatory Disease Center
Inflammatory Diseases Program

Dr. Albani studies the mechanisms of autoimmune diseases, and develops new strategies to re-direct T-cell responses.

Rolf Bodmer, Ph.D.

Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Director, Development and Aging Program

Dr. Bodmer focuses on the molecular mechanisms of organ formation and the genetic basis of heart development and performance.

Linda Bradley, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Inflammatory Diseases Program

Dr. Bradley is investigating parameters that control the development of immune cells and developing ways to modulate immune cell responses during infection and autoimmune diseases.

Sumit Chanda, Ph.D.

Associate Professor, Infectious and Inflammatory Disease Center
Inflammatory Diseases Program

Dr. Chanda's laboratory is working to elucidate the repertoire of host proteins required for host-pathogen interaction and viral propagation in influenza A and HIV.

Nicholas Cosford, Ph.D.

Associate Professor, NCI-Designated Cancer Center
Apoptosis and Cell Death Research Program

Dr. Cosford’s laboratory uses medicinal chemistry, chemical biology, rational drug design and microfluidic approaches to develop small-molecule modulators of cell death, survival and growth signaling pathways, for use as novel therapeutic agents to treat cancer, neurodegenerative and psychiatric disorders, and orphan diseases.

Sara A. Courtneidge, Ph.D.

Director of Academic Affairs
Professor, NCI-Designated Cancer Center
Director, Tumor Microenvironment Program

Dr. Courtneidge studies Src and its substrates and their roles in invadopodia/podosome formation, cancer progression and embryonic development.

Duc Dong, Ph.D.

Assistant Professor, Sanford Children’s Health Research Center
Genetic Disease Program

Dr. Dong’s group is working to decipher progenitor biology to gain insight into development and disease, and to enable genetic and pharmacologic manipulation of differentiation and regeneration.

Gregg Duester, Ph.D.

Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Development and Aging Program

Dr. Duester studies the function of the vitamin A metabolite retinoic acid during embryonic development, as a step toward understanding the causes and potential treatments of human birth defects.

Hudson Freeze, Ph.D.

Professor, Sanford Children’s Health Research Center
Director, Genetic Disease Program

Dr. Freeze focuses on identifying the genetic causes of Congenital Disorders of Glycosylation (CDG), and how these defects translate into disease presentation and treatment.

Adam Godzik, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Director, Bioinformatics and Systems Biology Program

Dr. Godzik's research uses computational and database methods to understand the relationships between protein sequence, structure and function

Dorit Hanein, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Bioinformatics and Systems Biology Program

Dr. Hanein's group employs electron microscopy, electron tomography and three-dimensional image analysis to determine the structures of macromolecular machines, ultimately in their native context and environment.

Malene Hansen, Ph.D.

Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Development and Aging Program

Dr. Hansen focuses on the modulation of aging and age-related diseases by evolutionarily conserved signaling pathways and newly identified longevity genes.

Rongsheng Jin, Ph.D.

Adjunct Assistant Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Degenerative Disease Research Program

Dr. Jin's interest is in the role of the NMDA receptor in synaptic plasticity and memory formation, and in brain injury and disease.

Marcus Kaul, Ph.D.

Assistant Professor, Infectious and Inflammatory Disease Center
Inflammatory Diseases Program

Dr. Kaul's work focuses on the role of chemokines, inflammatory cytokines and their receptors in inflammatory and degenerative diseases, including the promotion or prevention of HIV-associated neurodegeneration and dementia.

Sunyoung Lee, Ph.D.

Assistant Professor, NCI-Designated Cancer Center
Tumor Microenvironment Program

Dr. Lee focuses on how vascular endothelial growth factor (VEGF) regulates specification, morphogenesis, differentiation and homeostasis of blood vessels, both in normal and pathological conditions.

Fred Levine, M.D., Ph.D.

Professor & Director, Sanford Children’s Health Research Center
Genetic Disease Program

Dr. Levine studies the process of pancreatic beta-cell regeneration, with the goal of developing new therapies for diabetes.

Robert Liddington, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Director, Infectious Diseases Program

Dr. Liddington’s laboratory uses x-ray crystallography to explore the structural basis of host-pathogen interactions; the structure-function correlates of viral virulence; and the role of integrins in inflammation, hemostasis and cancer metastasis

Stuart Lipton, M.D., Ph.D.

Professor & Director, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Degenerative Disease Research Program

The Lipton laboratory studies molecular mechanisms of neurodegenerative diseases and stroke, including the role of excessive stimulation of ion channels and intracellular signaling pathways in nerve cells, develops new drug treatments for these conditions, and uses stem cells, molecularly engineered to become nerve cells, for cell-replacement therapy.

Francesca Marassi, Ph.D.

Associate Professor, NCI-Designated Cancer Center
Apoptosis and Cell Death Research Program

Dr. Marassi's laboratory uses solution-state and solid-state NMR spectroscopy to determine the three-dimensional structure of integral membrane proteins, which are potential therapeutic targets in cancer, heart disease and infectious disease.

Robert Margolis, Ph.D.

Professor, NCI-Designated Cancer Center
Tumor Development Program

Dr. Margolis' research focuses on the relationships between mitosis, the cell cycle, and the cellular cytoskeleton, and the regulatory mechanisms that control them.

Mark Mercola, Ph.D.

Professor, Sanford Children’s Health Research Center
Director, Muscle Development and Regeneration Program

Dr. Mercola's research is directed at discovering molecules that promote differentiation of cardiomyocyte progenitors that will ultimately be useful for regeneration of muscle cells that are lost in heart disease.

Jorge Moscat, Ph.D.

Professor, NCI-Designated Cancer Center
Tumor Microenvironment Program

Dr. Moscat studies the signaling mechanisms controlling cell growth and proliferation.

Christa Muller-Sieburg, Dr. rer. nat.

Professor, Del E. Webb Center for Neuroscience, Aging, and Stem Cell Research
Stem Cells and Regenerative Biology Program

Dr. Muller-Sieburg's research focuses on understanding the cellular and molecular mechanisms that regulate hematopoietic stem cells.

Timothy Osborne, Ph.D.

Professor, Diabetes and Obesity Research Center
Director, Metabolic Signaling and Disease Program

Dr. Osborne’s research examines how the body senses differences in the molecular composition of the diet to alter absorption and cellular metabolism, with a special emphasis on processes related to diabetes, obesity and atherosclerosis.

Robert Oshima, Ph.D.

Professor, NCI-Designated Cancer Center
Tumor Development Program

The Oshima laboratory investigates stem cells in breast cancer, colon cancer and human placenta development.

Andrei Osterman, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Bioinformatics and Systems Biology Program

Dr. Osterman’s research team uses a systems-biology approach to reconstruct and explore metabolic and transcriptional regulatory networks, and to predict and experimentally confirm new components of those networks.

Giovanni Paternostro, M.D., Ph.D.

Adjunct Assistant Professor, NCI-Designated Cancer Center
Apoptosis and Cell Death Research Program

Dr. Paternostro's laboratory is employing a multidisciplinary, systems-biology approach to identify optimal combinatorial drug therapies for cancer, and to understand the cardiac and metabolic alterations caused by aging and hypoxia.

Maurizio Pellecchia, Ph.D.

Professor, Infectious and Inflammatory Disease Center
Infectious Diseases Program

Dr. Pellecchia is working to characterize the three dimensional structures and intermolecular interactions of protein targets involved in cell-signaling, cancer cell transformation and virulence factors, and on combining medicinal chemistry with structure- and fragment-based drug design, to aid in the development of novel therapeutic compounds.

Manuel Perucho, Ph.D.

Adjunct Professor, NCI-Designated Cancer Center
Tumor Development Program

Dr. Perucho is studying the role of genetic and epigenetic alterations in the development of hereditary and nonhereditary gastrointestinal cancers.

Matthew Petroski, Ph.D.

Assistant Professor, NCI-Designated Cancer Center
Signal Transduction Program

Dr. Petroski studies how proteins are modified with ubiquitin and ubiquitin-like proteins.

Jeffrey Price, M.D., Ph.D.

Associate Professor, NCI-Designated Cancer Center
Signal Transduction Program

Dr. Price's laboratory is focused on the development of fully automated, quantitative microscopy, or scanning cytometry, for biomedical applications.

Pier Lorenzo Puri, M.D., Ph.D.

Associate Professor, Sanford Children’s Health Research Center
Muscle Development and Regeneration Program

Dr. Puri investigates the molecular mechanisms underlying the reprogramming of the genome during cell lineage commitment and terminal differentiation.

Tariq Rana, Ph.D.

Professor, Sanford Children’s Health Research Center
Director, RNA Biology Program

The Rana laboratory is studying the architecture and function of RNA Regulatory assemblies involved in stem cell creation and their fate decisions, RNA interference (RNAi), innate immunity, host-pathogen interactions, HIV-1 replication, and RNA therapeutics.

Barbara Ranscht, Ph.D.

Professor, NCI-Designated Cancer Center
Tumor Microenvironment Program

The research focus of the Ranscht laboratory is to understand the molecular basis of cell-cell communication in the nervous- and cardiovascular system, with special focus on the role of cell surface glycoproteins in the establishment and function of neuronal circuitries, and on cell surface receptors that mediate functions of the metabolic hormone adiponectin.

John C. Reed, M.D., Ph.D.

Adjunct Professor, NCI-Designated Cancer Center
Apoptosis and Cell Death Research Program

Dr. Reed’s laboratory studies the fundamental mechanisms of cell life-span regulation, how the defective regulation of programmed cell death mechanisms result in disease, and the role of NLR-family proteins in innate immunity, inflammation and infectious disease.

Robert Rickert, Ph.D.

Associate Dean, Graduate Program
Professor, Infectious and Inflammatory Disease Center
Director, Inflammatory Diseases Program

Dr. Rickert's laboratory is working to better understand the molecular determinants of B lymphocyte differentiation in normal and disease states.

Stefan Riedl, Ph.D.

Associate Professor, NCI-Designated Cancer Center
Apoptosis and Cell Death Research Program

Dr. Riedl research is centered on understanding the structure and mechanisms of signaling proteins as well as their complexes and signaling platforms in light of pathway regulation and disease.

Ze'ev Ronai, Ph.D.

Scientific Director, Sanford-Burnham Medical Research Institute at La Jolla
Professor & Associate Director, NCI-Designated Cancer Center
Director, Signal Transduction Program

Dr. Ronai's group is working to understand the regulation and function of mammalian stress-response signaling pathways.