The Exploratory Pharmacology facility conducts a variety of industry-standard experiments to assess the drug-like properties of compounds including in vitro
assays of compound stability, absorption, distribution, metabolism, excretion and toxicity (ADME/T). The core also supports the development of novel compounds for use in vivo
applications by performing excipient screening, formulation studies, dose-ranging, tissue distribution studies, and comprehensive drug metabolism and pharmacokinetics (DMPK) studies. The core combines state-of the-art technology, including those listed below, and the expertise of academic and industry-savvy investigators to analyze and interpret the data to advance to most promising compounds.