The Cardiometabolic Phenotyping Core facility (CMPC) provides researchers with a wide array of methodologies and techniques to evaluate cardiovascular and metabolic functions in mice. The CMPC also conducts specialized cardiovascular surgeries to establish disease models in mice. Imaging modalities (high resolution ultrasound and optical imaging) performed by the CMPC have utility to interrogate wide-ranging biological targets/disease indications. Centralization of this expertise and technology in the CMPC offers a standardized, efficient and cost-effective means to deliver high-quality phenotyping and surgical services. As needed, CMPC staff will assist in the design of experimental studies. Moreover, the CMPC staff will monitor the emerging needs of investigators and expand our repertoire of services accordingly.