The high-throughput screening (HTS) assay development team provides support for the design and development of new HTS assays as well as optimization support for existing assays. In Lake Nona in Orlando, the facility shares space with the ultra-high-throughput (uHT) screening center
which houses the modular HighRes screening system instrumentation. The system may be used in workstation mode by the facility team for seemless implementation of assays within the fully integrated system together with the uHTS team. The assay development team is skilled in various screening modalities, to help with selection and development of assays most suitable to each particular project. The team also provides support in the design of optimal structure-activity relationship (SAR) panels, development of supporting assays, data analysis, and interpretation for studies aimed at characterization and optimization of hits obtained in primary HTS.
The facility is a part of Conrad Prebys Center for Chemical Genomics
and can advise and help in preparation of data packages for screening-related grants.