Stem Cell and Regenerative Biology

A new stem cell enters the mix

A new stem cell enters the mix

Dr. Evan Snyder and his team generated a new type of stem cell that’s easier to produce and shows therapeutic benefit in a rodent stroke model.

How to make new neurons

How to make new neurons

Dr. Stuart Lipton and collaborators found a way to reprogram human skin cells directly into functioning neurons—a first step in creating personalized therapies for Alzheimer’s disease and other neurological disorders.

What is “Disease in a Dish?”

What is “Disease in a Dish?”

Learn more about this state-of-the-art stem cell technology and how it’s being used to better understand disease and discover new medicines.

Studying stem cells and regenerative biology

Scientists in the Stem Cells and Regenerative Biology Program are working to understand the biology of embryonic stem cells, which give rise to the many different types of cells of the body, and adult stem cells, which reside in many tissues as reservoirs of regeneration and repair. They are also studying how to reprogram adult cells of any tissue type into induced pluripotent stem cells, a specially engineered type of stem cell that have a lot in common with their embryonic cousins.

Researchers in this program are working to fully understand the role that stem cells play:

  • During the earliest stages of development when organs and tissues first form
  • During normal physiology (tissue homeostasis)
  • When early development goes awry and abnormalities arise
  • During the onset of cancer (oncogenesis)
  • During degeneration and aging

How our research helps improve health

At the same time researchers are unraveling basic stem cell biology in human development, they are also harnessing stem cell technology to regenerate or replace diseased or damaged tissue. In addition, our scientist are using induced pluripotent stem cells to model diseases in a dish and applying these models to better understand disease and test new treatments.

Research - Neuroscience, Aging and Stem Cell - Stem Cell and Regenerative Biology: How Our Research Helps

Recent Developments

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Stem cell “Collaboratory” opens in La Jolla

On November 29, scientific and community leaders gathered to celebrate the grand opening of the Sanford Consortium for Regenerative Medicine, a "Collaboratory" that brings five of the world's leading stem cell research institutions together into one state-of-the-art facility.  Read More...

More about the program

Evan Snyder

Evan Snyder, M.D., Ph.D., director of the Stem Cells and Regenerative Biology Program, talks about stem cells as the fundamental makeup of an organism. He and others in the program hope to better understand how these cells help maintain an organism’s well-being throughout life in order to invoke the same principles to combat human diseases.

Recent Publications

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Research - Neuroscience, Aging and Stem Cell - Stem Cell and Regenerative Biology: Recent Publications
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