Diabetes and Obesity Research Center

New TRI Facility Opens in Orlando

New TRI Facility Opens in Orlando

The Florida Hospital – Sanford-Burnham Translational Research Institute for Metabolism and Diabetes is dedicated to the advancement of a new paradigm of personalized approaches to researching and treating diabetes and obesity.

Obesity Research Advances to Clinical Testing

Obesity Research Advances to Clinical Testing

Sanford-Burnham researchers discovered that orexin, a hormone produced in the brain, activates calorie-burning brown fat in mice. Orexin research is now advancing to the TRI for clinical testing.

Personalized Medicine Partnership of Florida

Personalized Medicine Partnership of Florida

Sanford-Burnham is partnering with Moffitt Cancer Center and Florida Hospital to research the development of new personalized treatments in cancer and metabolic diseases.

Takeda Partnership Midterm Update

Takeda Partnership Midterm Update

Sanford-Burnham's collaboration with Takeda Pharmaceutical and Florida Hospital aims to discover new therapeutic approaches to treat obesity.

About the Diabetes and Obesity Center

Our scientists seek to explore the metabolic basis of disease and to rapidly translate discovery to clinical care by leveraging the bridges we have built with clinical partners.

- Daniel Kelly, M.D.

Scientific Director, Sanford-Burnham at Lake Nona

TRI opensNew TRI facility opens in Orlando

Type 2 diabetes, which is driven by obesity, has increased nearly 30 percent in the last decade, with more than 60 percent of U.S. adults diagnosed as overweight or obese. To address these challenges, scientists in the Diabetes and Obesity Research Center are studying the metabolic basis of obesity-related diabetes and its cardiovascular complications. The center is focused on translational research and has established advanced technology resources and formed clinical and pharmaceutical research partnerships to drive their discoveries toward patient application.

Read on to learn more about our scientific programs, drug discovery capabilities, and shared resources, or visit our blog for frequent updates.

Learn more about our diabetes and obesity research in the following fields:

Research - Diabetes and Obesity: About

Recent Developments

Diabetes and Obesity Research Programs

The Diabetes and Obesity Research Center uses a multi-disciplinary approach to study the complex interactions of common metabolic diseases and corresponding cardiovascular complications. Scientists are interested in fundamental questions about disease: What happens when the brain-body “crosstalk” fails? How does a person’s genetic background and metabolic make-up dictate the development of obesity and the onset and severity of diabetes? How do errors in fuel burning contribute to the development of metabolic disease? Why is heart disease more difficult to treat in diabetics than heart disease in non-diabetics?

Sign In Skip Navigation Links Skip navigation links
Our Mission
Research
Talent
Technology
Training & Education
Our Supporters
Privacy Policy