Neuroscience and Aging Research Center

Sanford-Burnham and Intrexon Corp. establish collaboration to accelerate stem cell research

Sanford-Burnham and Intrexon Corp. establish collaboration to accelerate stem cell research

New collaboration combines Sanford-Burnham’s renowned scientific team and Intrexon’s proprietary discovery platforms to accelerate human iPSC research.

Sanford-Burnham research projects selected to go to space

Sanford-Burnham research projects selected to go to space

Space Florida to send two experiments from Sanford-Burnham Medical Research Institute to the International Space Station.

Searching for causes of neuron death in Alzheimer’s and TBI

Searching for causes of neuron death in Alzheimer’s and TBI

Sanford-Burnham researchers discovered that the protein appoptosin prompts neurons to commit suicide in several neurological conditions.

About the Neuroscience and Aging Research Center


At our center we have two approaches…we want to protect cells in the brain, particularly nerve cells, from a variety of neurodegenerative diseases like Alzheimer’s and Parkinson’s and we’re also trying to regenerate neurons and associated cells.

- Stuart Lipton, M.D., Ph.D.

Professor and Director,
Neuroscience and Aging Research Center

The Neuroscience and Aging Research Center is focused on producing new treatments for neurologic and cardiac diseases associated with aging and development, including Alzheimer’s, Parkinson’s, Lou Gehrig’s, Autism, vascular (stroke), macular degeneration, and diabetic diseases. We use findings from basic molecular research and apply a systems approach to translate the discoveries into clinical applications.

Principle investigators are working in the areas of neurodegenerative diseases, cardiac diseases, and diabetes. Our scientists use both drug and regenerative medicine (stem cell) approaches.

What are the goals and activities of the Center?

Our Center translates basic science discoveries into new treatments to extend lifespan and to combat degenerative disorders associated with aging or development, including Alzheimer’s disease, Parkinson’s disease, stroke, Autism and others.
  • We are developing biomarkers and novel drug treatments for neurodegenerative and cardiac diseases with NIH Translational Grants
  • We are developing stem cell-based therapies for stroke and Parkinson’s disease with CIRM Translational Grants
  • Under the auspices of an NIH P01 Program Project Grant, we are studying the links between Down syndrome and Alzheimer’s disease to develop new treatments to improve cognition in both disorders
  • We are leveraging our NINDS/NIH Neuroscience P30 Center Core Grant to perform high-throughput screens for new therapies for Alzheimer’s, Parkinson’s, and Autism. These drugs designed to protect synapses, the connections between nerve cells that mediate movement, memory and cognition
  • We are forming ties with clinical/translational partners in order to test new therapies in human trials


Recent Developments

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