Infectious and Inflammatory Disease Center

How the body fends off bacteria

How the body fends off bacteria

Researchers have shed new light on how the body protects itself from foreign invaders, advancing knowledge that’s key to the design of new therapeutics.

Mining the microbiome with Scott Peterson

Mining the microbiome with Scott Peterson

Scott Peterson, Ph.D. is a little different from most biomedical researchers. He doesn’t just want to know what goes wrong when we get sick—he’d rather know what makes us healthy.

Researchers find new anti-malarial drug target

Researchers find new anti-malarial drug target

An international team of scientists has identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria.

About the Infectious and Inflammatory Disease Center

There are a number of scientists here whose work is really on the verge of being translated into the clinic. I want to promote that as much as possible.

- Carl Ware, Ph D.

Director of the Infectious and Inflammatory Disease Center

Infectious diseases such as HIV/AIDS and tuberculosis continue to rank high among global mortality factors, especially in developing countries, and systemic inflammation has been identified as a root case of many chronic disorders in the developed world. The IIDC’s mission is to map the molecular intricacies of the immune system and pathogen cells and apply this knowledge to generate new therapeutics for autoimmune diseases, infection and cancer.

What are the goals and activities of the Center?

The primary mission of the IIDC is directed at understanding the fundamental mechanisms of inflammation and immunity as the underlying processes essential to host defense and cancer, and the cause of pathologic tissue destruction in autoimmune disease.

The IIDC has made significant strides in developing translational opportunities with a focus on bringing novel therapeutics forward to clinical trials. These opportunities encompass collaborations with pharma as well funding through the NIH.

We use a “team pathway” approach to create comprehensive studies that harness the creativity of our Sanford-Burnham faculty. Our research efforts include functional screening technologies to identify disease-driving genes and pathways in autoimmune and infectious diseases and cancer. We employ bioinformatics with human genetics and clinical informatics to create a complete organizational structure that can provide novel therapeutics for clinical trials.

The IIDC’s overall approach affords Sanford-Burnham the opportunity to bring a complete package for licensing or spin-out of a for-profit enterprise.

Recent Developments

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