Cancer Metabolism, Autophagy, & Nutrient Sensing Symposium

Cancer Metabolism, Autophagy, and Nutrient Sensing Symposium

June 25-26, 2014
Sanford-Burnham Medical Research Institute
La Jolla, California


Location 1

Fishman Auditorium map, 10901 N. Torrey Pines Road, La Jolla, CA 92037

Location 2

Building 12 Auditorium map, 10905 Road to the Cure, La Jolla, CA 92121

Seating: Please note that seating for the live event in the Fishman Auditorium is on a first-come, first-served basis. Due to the limited seating in the Fishman, there will be overflow seating outside in the Foyer, and the talks will also be simulcast to our large and comfortable Building 12 Auditorium located at 10905 Road to the Cure, San Diego, CA 92121.

Parking: For the Fishman, please park on the street or in the SB parking garage on campus, and report to the B1 receptionist for directions to the auditorium (if you are not familiar with the location). For the B12 Auditorium, please park in the dirt parking lot directly across from the building on the Road to the Cure.



This symposium is organized by:


Coordinator (for all inquiries):
Kathleen Alexander Juran

Symposium Flyer

8.5"x11"
11"x17"

Wednesday, June 25

4:15 pm - Registration

5:00 - Welcome: Jorge Moscat

Introductory Notes/Remarks – Kristiina Vuori




Keynote Presentation


Larry Goldstein

The VHL Tumor Suppressor Protein: Insights into Oxygen Sensing and Cancer Metabolism


William Kaelin
Dana Farber Cancer Institute, Boston




5:50 pm


Larry Goldstein

Autophagy, Metabolism, and Pancreatic Cancer


Alec Kimmelman
Harvard Medical School, Boston



Thursday, June 26

7:45 am - Coffee Service

8:00 am


Larry Goldstein

Regulation of autophagy by oncogenic signals


Beth Levine
Howard Hughes Medical Institute, University of Texas - Southwestern Medical Center, Dallas



8:35 am


Larry Goldstein

AMPK and mTOR in nutrient sensing and autophagy regulation


Kun-Liang Guan
University of California, San Diego



9:10 am


mTORC1 activation by p62


Jorge Moscat
Sanford-Burnham Medical Research Institute





9:45 am - Coffee Break




10:15 am


Larry Goldstein

Regulation of Cancer Cell Growth & Survival by mTOR/S6K1 Signaling


John Blenis
Harvard Medical School, Boston



10:50 am


Metabolic reprograming by the mTORC1/p62 complex in the tumor stroma


Maria Diaz-Meco
Sanford-Burnham Medical Research Institute



11:25 am


Larry Goldstein

Inflammation, metabolism and liver cancer


Michael Karin
University of California, San Diego





12:00 pm - Break




1:30 pm


Larry Goldstein

Hypoxia, Metastasis, and Tumor Progression


Celeste Simon
Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia



2:05 pm


Larry Goldstein

Analysis of metabolic pathways in cancer cells and tumors


Ralph J. DeBerardinis
University of Texas - Southwestern Medical Center, Dallas



2:40 pm


Larry Goldstein

Autophagy and neurodegeneration


David Rubinsztein
Cambridge Institute for Medical Research, Cambridge, UK





3:15 - Coffee Break




3:45 pm


Larry Goldstein

Nutrients supporting mitochondrial metabolism and cellular redox


Christian Metallo
University of California, San Diego



4:20 pm


Larry Goldstein

Myc and Metabolism on the Path to Cancer


Chi Van Dang
University of Pennsylvania - Abramson Cancer Center, Philadelphia



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About the Cancer Center
Shared NCI Cancer Centers Council (C3) cores at nearby Centers
Cancer Metabolism, Autophagy, & Nutrient Sensing Symposium
Cell Death and Survival Networks
Progress on the Path to Cancer Cures
Tumor Initiation and Maintenance
Tumor Microenvironment and Metastasis
Cancer Center Postdoc/Grad Student Retreat - July 30, 2014
Cancer Center Shared Resources
Sanford-Burnham Cancer Metabolism Symposium
Chemical Biology and Drug Discovery
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