2011 Sanford-Burnham Annual Symposium

33rd Annual Sanford-Burnham Symposium

Structural Systems Biology

June 7, 2011
9 a.m. – 5:15 p.m. PT
La Jolla, California


The 2011 Sanford-Burnham Symposium is organized by the faculty of the Program on Bioinformatics and Systems Biology to explore the emerging synergy between structural and systems biology.

Systems biology aims to provide meaningful models capable of quantitative and predictive descriptions of cellular processes. At the same time, structural biology, boosted by technological developments, is approaching a point where three-dimensional information is available for all players of a biological network. We believe that the marriage between systems biology and structural biology—“structural systems biology”—will be an ideal vehicle for integrating various types of information coming from high-throughput biology, high-end structural methodologies, and classical biological approaches.

What is possible now for model systems, mostly small bacteria, will soon become routine for human- and disease-model cells, opening an avenue to a better understanding of disease processes integrating the high-resolution structural- and system-level understanding. In this symposium, we want to bring together leading researchers from both fields to explore the synergy between them.

Speakers

John Reed, M.D., Ph.D.

CEO, Sanford-Burnham Medical Research Institute

Opening Address


Sir John Walker, Ph.D.

Director, MRC Mitochondrial Biology Unit Cambridge

Understanding the structures of inner membrane proteins in the context of mitochondria


Andrei Sali, Ph.D.

Director, California Institute for Quantitative Biosciences

University of California, San Francisco

Determining architectures of macromolecular assemblies by aligning interaction networks to electron microscopy density maps


Jim Wells, Ph.D.

Professor

University of California, San Francisco

Understanding caspase action through systems-wide approaches


Rob Russell, Ph.D.

Professor

University of Heidelberg

Structures in systems biology: adding mechanism to interaction networks


Peer Bork, Ph.D.

Professor

European Molecular Biology Laboratory, Heidelberg

Systemic analysis of unicellular organisms: a role for structural biology


Alex Hoffman, Ph.D.

Professor

University of California, San Diego Signaling Systems Laboratory

Biophysics meets systems biology in the control of NFkB


Art Olson, Ph.D.

Director, Molecular Graphics Laboratory

The Scripps Research Institute

Interacting with protein interactions


Nitin Baliga, Ph.D.

Professor
Institute for Systems Biology

Systems approaches to tackle biological complexity


Panel Discussion

Synergies between structural and systems biology


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