The Burnham Institute for Medical Research (Burnham) and the University of California, Santa Barbara (UCSB) have named leading biomedical researcher Jamey D. Marth director of a new joint Center for Nanomedicine that will be established at UCSB.
The collaborative biomedical research partnership merges UCSB’s core expertise in engineering, materials sciences, nanotechnology and physics with Burnham’s strengths in the biological sciences and biomedical research. The new center will promote the convergence of these fields and pioneer the development of novel technologies for advancing human health. Together, UCSB and Burnham plan to recruit additional scientists to the Center for Nanomedicine to create collaborative research teams that will produce innovative technologies for an entirely new generation of biosensors, medical devices, drug delivery nanoparticles, instruments for advanced biomedical research, and other products. Nanomedicine, an offshoot of nanotechnology, refers to highly specific medical intervention at the molecular scale for curing disease or repairing damaged tissues, such as bone, muscle, or nerve.
“Interdisciplinary nanotechnologies are vital to establishing a holistic and rigorous approach to biomedical research that encompasses disparate knowledge and integrates all of the cellular molecules and factors that contribute to disease,” said Marth, who joined UCSB’s faculty in the Department of Molecular, Cellular, and Developmental Biology (MCDB), as well as Burnham’s faculty, on July 1.
At UCSB, Marth has been appointed to two prestigious endowed professorships. He is the first recipient of both the John Carbon Chair in Biochemistry and Molecular Biology and the Duncan and Suzanne Mellichamp Chair in Systems Biology in the campus’s Biomolecular Science and Engineering Program. Prior to joining Burnham and UCSB, Marth was professor of cellular and molecular medicine and Howard Hughes Medical Institute Investigator at the UC San Diego School of Medicine.
“With appointments to both UCSB and Burnham, I look forward to building further bridges between the talented scientists at these institutions and to promoting our joint efforts to develop nanotechnologies for disease diagnosis, prevention, therapy, and cure,” said Marth. “This new and timely initiative will require the expertise of engineers, physicists, bioinformatics experts, and materials scientists working in close collaboration with biologists, that builds on the complementary expertise that exists at UCSB and the Burnham Institute for Medical Research.”
Marth’s laboratory is world-renowned in the application of cellular biology to uncovering the origins of disease. His research includes an integrative approach to combine genomics, proteomics, glycomics and lipidomics in a holistic and rigorous way to understand disease. By integrating these four fundamental components of all cells in biomedical research, his laboratory has defined new mechanisms that span common and grievous disease syndromes including autoimmune disease, infectious disease, and Type 2 diabetes.
“We are pleased to welcome an elite scientist like Dr. Marth to Burnham and to this collaborative partnership with UCSB in the exciting field of nanomedicine,” said Dr. John Reed, Burnham’s president and chief executive officer and professor and Donald Bren Presidential Chair at the institute. “The impact of our collaborative efforts will be far-reaching, not only in terms of advancing the science of nanomedicine, but in terms of economic development opportunities for new company generation and job creation.”
Pierre Wiltzius, Worster Dean of Science and professor of physics at UCSB, noted that “the coupling of biomolecules to nanomaterials and their assembly into nanostructures will produce a wide range of ‘smart’ devices with an enormous breadth of practical applications, including diagnostics and biosensors, drug screening and delivery, tissue engineering, and much more.” Wiltzius added: “The impact of this new field of science, termed nanomedicine, on medicine and life sciences will be hugely transformative, comparable in magnitude to the transition from transistors to silicon chips in the computer sciences.”
Larry Coldren, acting dean of UCSB’s College of Engineering and Kavli Professor of Optoelectronics and Sensors, described the collaborative opportunities in nanomedicine and systems biology presented by the new center as a “perfect complement” to research underway at UCSB on networked systems approaches to drug development and therapies. “The combination of Jamey Marth’s interests in disease mechanisms with our strengths in bioengineering and computational and materials sciences will be highly synergistic, and could well lead to major advances in therapies for grievous human diseases,” he said.
Burnham established an affiliation with UCSB in 2006, led by internationally renowned biomedical researcher Erkki Ruoslahti, M.D., Ph.D. Dr. Ruoslahti maintained his primary appointment as Distinguished Professor with Burnham and joined UCSB’s Department of Molecular, Cellular, and Developmental Biology as an adjunct Distinguished Professor. This type of collaboration, involving a highly ranked university and a nonprofit, independent research institute, exemplifies the inherent value of interdisciplinary research and the enhanced potential created when two such entities join forces.
“Professor Marth will invigorate interdisciplinary biomedical research at UC Santa Barbara, not only with his own exciting research in the Molecular, Cellular and Developmental Biology Department, but also with expansion of the Burnham Institute at UCSB,” said Dennis O. Clegg, co-director of UCSB’s Center for Stem Cell Biology and Engineering and professor and recent past chair of MCDB. “Burnham is one the premier forces in medical research in the world, and expansion of the partnership with UCSB will enable novel approaches to uncover the molecular mechanisms of disease.”