Carl Ware, Ph.D., has been appointed director of the Infectious and Inflammatory Disease Center (IIDC) at Sanford-Burnham Medical Research Institute (Sanford-Burnham). As director, he will oversee the Institute’s work on HIV, influenza, anthrax, rheumatoid arthritis, Crohn’s disease, autoimmune disorders and many other conditions.
“I am excited to be at Sanford-Burnham,” said Dr. Ware. “I have always been impressed by the collaborative environment here. In addition to being an excellent place to conduct research, there are also incredible resources to move the science forward towards new therapies.”
Dr. Ware’s research focuses on the fundamental pathways that control cytokines, a family of small proteins involved in immune signaling. One cytokine, called tumor necrosis factor or TNF, is part of an important communications network between cells in the immune system. Dr. Ware’s research on cytokines has led to two drugs now in clinical trials. He is also interested in how pathogens regulate the human immune system to gain a competitive advantage.
“We are very pleased that Carl has joined us at Sanford-Burnham,” said CEO John Reed, M.D., Ph.D., professor and Donald Bren Chief Executive Chair. “His insights into immune signaling and inflammation and his proven track record of translating basic research findings into new treatments will make a significant impact on our work in autoimmune, inflammatory, infectious and other diseases.”
As director, Dr. Ware will provide scientific vision and leadership for the center. He plans to build the Institute’s ability to combat viral diseases and create partnerships with pharmaceutical and biotech companies to find new treatments for immune-based conditions, such as rheumatoid arthritis, lupus and lymphoma.
“There are many scientists here at Sanford-Burnham whose work is poised for translation to the clinic,” said Dr. Ware. “I want to promote translating lab discoveries into treatments as much as possible.”
Prior to joining Sanford-Burnham, Dr. Ware headed the Division of Molecular Immunology at the La Jolla Institute for Allergy & Immunology, where he had been a researcher since 1996. Before that, he was a professor of Immunology at UC Riverside. Dr. Ware earned his Ph.D. in Molecular Biology and Biochemistry at UC Irvine and conducted his postdoctoral research at UC Irvine, the University of Texas and Dana Farber Cancer Institute.