http://www.burnham.org The latest Burnham medical research news en-us http://www.burnham.org/rss.gif http://www.burnham.org 90 24 http://www.burnham.org/default.asp?contentID=716 April 17, 2009 -- Burnham Institute for Medical Research (Burnham) is pleased to announce that five of its postdoctoral fellows will present seven papers on their data at the American Association for Cancer Research (AACR) 100th Annual Meeting 2009. http://www.burnham.org/default.asp?contentID=697 March 18, 2009 -- Investigators at Burnham Institute for Medical Research (Burnham) have learned that a protein called Shp2 plays a critical role in the pathways that control decisions for differentiation or self-renewal in both human embryonic stem cells (hESCs) and mouse embryonic stem cells (mESCs). http://www.burnham.org/default.asp?contentID=688 February 22, 2009--Researchers at the Dana-Farber Cancer Institute, Burnham Institute for Medical Research and the Centers for Disease Control and Prevention have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented range of influenza A viruses, including avian influenza A (H5N1) virus, previous pandemic influenza viruses, and some seasonal influenza viruses. These antibodies have the potential for use in combination with other treatments to prevent or treat certain types of avian and seasonal flu. http://www.burnham.org/default.asp?contentID=686 LA JOLLA, Calif., February 12, 2009—Taking clues from their stem cell research, investigators at the University of California San Diego and Burnham Institute for Medical Research have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes. http://www.burnham.org/default.asp?contentID=673 LA JOLLA, Calif., January 9, 2009 -- Researchers at the Burnham Institute for Medical Research have shown that search algorithms used in digital communications can help scientists identify effective multi-drug combinations. http://www.burnham.org/default.asp?contentID=672 LA JOLLA, Calif., January 5, 2009-- Scientists at Burnham Institute for Medical Research have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell death). http://www.burnham.org/default.asp?contentID=671 LA JOLLA, Calif., January 5, 2008—Scientists at Burnham Institute for Medical Research have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair. Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies. http://www.orlandosentinel.com/news/local/orange/orl-burnham0408dec21,0,6537698.story ORLANDO SENTINEL, Dec. 21 -- They've left prestigious universities and long-held research positions. Often moving across the country, a team of scientists has converged on Orlando in recent months, unpacking their test tubes and getting to work at the Burnham Institute for Medical Research. http://www.burnham.org/default.asp?contentID=647 The National Institute of Allergy and Infectious Diseases estimates that up to 45 percent of deaths in the developed world involve chronic fibrotic processes. Under a patent license from the Burnham Institute for Medical Research (Burnham) in which Burnham researcher Dr. Erkki Ruoslahti is a named inventor, Genzyme Corporation is conducting clinical trials on GC-1008, an anti-fibrotic drug. http://www.burnham.org/default.asp?contentID=643 LA JOLLA, Calif., December 1, 2008—Researchers at the Burnham Institute for Medical Research have shown in both fruit flies and humans that genes involved in embryonic heart development are also integral to adult heart function. The study, led by Rolf Bodmer, Ph.D., was published in Proceedings of National Academy of Sciences. http://www.burnham.org/default.asp?contentID=639 LA JOLLA, Calif., November 12, 2008 -- Burnham Institute for Medical Research announced the election of five new members to its board of trustees. These new trustees bring a wide variety of business, legal and philanthropic experience to Burnham. http://www.burnham.org/default.asp?contentID=638 LA JOLLA, Calif., October 13, 2008 -- Burnham Institute for Medical Research today announced that five of the Institute’s postdoctoral research associates will be honored with Fishman Fund Awards to recognize their commitment to basic biomedical research. The awardees will receive $5,000 grants to be used to further their education and career development. http://www.burnham.org/default.asp?contentID=633 LA JOLLA, Calif., October 7, 2008 -- Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. The research, which was published as the featured article in the October 7 edition of Cancer Cell, may lead to new cancer treatments. http://www.burnham.org/default.asp?contentID=631 LA JOLLA, Calif., Oct. 2, 2008 -- The Salk Institute for Biological Studies and Burnham Institute for Medical Research today announced the identification of 295 host cell factors that are involved in human immunodeficiency virus (HIV) infection. The study, published in the Oct. 3 issue of Cell, could lead to the development of a new class of HIV therapeutics aimed at disrupting the human-HIV interactions that lead to viral infection. http://www.burnham.org/default.asp?contentID=614 LA JOLLA, Calif., September 16, 2008 -- Burnham Institute for Medical Research today announced that Stuart A. Lipton, M.D., Ph.D., professor and director of the Del E. Webb Neuroscience, Aging, and Stem Cell Research Center at Burnham has been awarded $8 million, over five years, to establish a Center for Neurodegeneration Science (CNS). The center will study potential environmental causes of Parkinson’s disease. Funding for the center comes from the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health.